Laurie Brenchley

IgG sequencing maps systemic antibody binding to oral commensals and pathobionts in health and periodontitis

This study uses IgG sequencing to map antibody binding to oral microbes in health and periodontitis, revealing disease-specific changes in systemic immune recognition.

Mucosal Inflammation Shapes Human Neutrophil States in Tissue and Circulation

This study identifies tissue-specific neutrophil states in oral mucosa and circulation, showing how periodontitis alters their function and affects systemic neutrophil states.

Single-cell atlas of human oral mucosa reveals a stromal-neutrophil axis regulating tissue immunity in health and inflammatory disease

This paper constructs a single-cell transcriptome atlas of human oral mucosa in health and periodontitis, identifying a stromal-neutrophil axis regulating tissue immunity.