Nicolas Jean Bouladoux

This study uses IgG sequencing to map antibody binding to oral microbes in health and periodontitis, revealing disease-specific changes in systemic immune recognition.

This study identifies SlyB as a key lipoprotein in Yersinia pestis that enhances envelope stress tolerance, enabling immune evasion in mammalian hosts but not in flea vectors.

This study shows a ketogenic diet reprograms host and microbiome functions to enhance tissue regeneration through IL-17A activation and microbial riboflavin and sphingomyelinase pathways.

This study identifies a dominant population of IL-10-producing, T-bet-expressing CD4+ Tr1 cells in the small intestine that are shaped by dietary antigens rather than the microbiota.

This study shows that sulfide is essential for gut microbial and immune homeostasis, with its depletion causing immune dysfunction and impaired vaccine response.

The paper shows that mild detergent exposure reactivates retroelements, inducing CD8+ T cells that enhance skin wound repair through IL-17A.

This study identifies a neuroimmune CGRP-RAMP1 axis that modulates cutaneous adaptive immunity to the microbiota by constraining Type 17 responses and limiting T cell activation.