DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169
Vijay Menon, Varsha Ananthapadmanabhan, Selene K. Swanson, Siddharth Saini, Fatmata F. Sesay, Vasily A. Yakovlev, Laurence A. Florens, James A. DeCaprio, Michael P. Washburn, Mikhail G. Dozmorov, Larisa Litovchick
This paper identifies DYRK1A's role in DNA repair by regulating RNF169-mediated 53BP1 recruitment to DSB sites, with implications for DNA damage therapy response.
Cell Cycle · Feb 17, 2019Peer-reviewedMolecular Biology