First landscape of binding to chromosomes for a domesticated mariner transposase in the human genome: diversity of genomic targets of SETMAR isoforms in two colorectal cell lines
Aymeric Antoine-Lorquin, Ahmed Arnaoty, Sassan Asgari B, Martine Batailler, Linda Beauclair, Catherine Belleannée, Solenne Bire, Nicolas Buisine, Vincent Coustham, Alban Girault, Serge Guyétant, Thierry Lecomte, Benoît Piégu, Bruno Pitard, Isabelle Stévant, Yves Bigot
The paper identifies chromosomal binding targets of SETMAR isoforms in colorectal cell lines and finds isoform-specific binding to Hsmar1 ends and non-conserved sites, with differing expression profiles between cell lines and tissues.
bioRxiv · Mar 9, 2017 · PreprintGenomics