Spatiotemporal localization and activity of mitochondria regulate actomyosin contractility in Drosophila gastrulation
Somya Madan, Sayali Chowdhary, Sakshi Phalke, Harsh Mittal, Manos Mavrakis, Richa Rikhy
This study shows that mitochondrial redistribution and activity are crucial for apical constriction in Drosophila gastrulation, regulated by the Dorsal signaling pathway.
bioRxiv · Sep 5, 2025 · PreprintDevelopmental Biology