Author

Yaw Asante

Case Western Reserve UniversityORCID 0000-0002-6924-8632Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Berkley E. GryderiD· 2 shared Alexander J. Federation· 1 shared Ana María Garzón PorrasiD· 1 shared Bhavatharini UdhayakumariD· 1 shared Carrietta Farma-Hai· 1 shared Diana H. ChiniD· 1 shared Elena-Loredana Rotariu· 1 shared Jordyn Kelly· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Berkley E. GryderORCID

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2 papers

Recent·Most cited

Rare RNA Polymerase II failure modes mark the cancer-driving genes most affected by epigenetic perturbation

Yaw Asante, Berkley E. Gryder

The paper introduces compPASS, a tool to identify Pol2 failure modes in cancer, revealing rare modes linked to gene regulation and therapy response.

bioRxiv · May 31, 2026 · PreprintBioinformatics

CpG island density predicts CBP/p300 dependency across 3D chromatin clusters

Md Imdadul H. Khan, Matthew S. Chang, Yaw Asante, Maya Al-Haddad, Teagan Kukhta, Bhavatharini Udhayakumar, Ana María Garzón Porras, Elena-Loredana Rotariu, Saanvi Aneja, Jordyn Kelly, Carrietta Farma-Hai, Kavi Ullal, Diana H. Chin, Alexander J. Federation, Lindsay K. Pino, , Berkley E. Gryder

The paper identifies two classes of Pol2-mediated chromatin clusters and shows CpG island density predicts CBP/p300 dependency.

bioRxiv · May 7, 2026 · PreprintCancer Biology