Author

Manuel Esguerra

University of MinnesotaORCID 0000-0002-6934-5424Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Organism:rat· 1

Frequent Co-Authors

Alik S. WidgeiD· 1 shared Bradley AngstadtiD· 1 shared Elizabeth M. SachseiD· 1 shared Evan M. Dastin-van RijniD· 1 shared Francesca A. Iacobucci· 1 shared Jonathan P Bennek· 1 shared Megan E. MensingeriD· 1 shared Michelle C. BucciniiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperNeuroscience

Alik S. WidgeORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintApr 8, 2026

mPFC axons drive cognitive control enhancement during striatal stimulation

Elizabeth M. Sachse, Evan M. Dastin-van Rijn, Jonathan P Bennek…·Alik S. Widge

This study shows that optogenetic stimulation of mPFC axons, not midSTR neurons, enhances cognitive control in a rodent Set-Shift task, suggesting mPFC axons are key drivers of DBS therapeutic effects.

1 citation

ratelectronic health records