Author

Elizabeth Tweedie Ables

East Carolina UniversityORCID 0000-0002-6934-9302Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:Drosophila· 5 Approach:experimental assay· 5 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Amanda M. PowelliD· 3 shared Anna E. WilliamsiD· 3 shared Danielle S. Finger· 2 shared Alexandria Warren· 1 shared Allison C. Simmons· 1 shared Allison N. BeachumiD· 1 shared Ally SolomoniD· 1 shared BiClaireline Cesar· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersDevelopmental Biology

Amanda M. PowellORCID

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5 papers

Recent·Most cited

Ecdysone Receptor autonomously controls germ cell differentiation in the Drosophila ovary

Lauren E. Jung, Alexandria Warren, Changhong Yin, Weihua Huang, Allison C. Simmons, Samantha I McDonald, Lindsay A. Swain, Victoria E. Garrido, Daniel N. Phipps, BiClaireline Cesar, Danielle S. Finger, Zhipeng Sun, Todd G. Nystul, Elizabeth Tweedie Ables

This study shows that the Ecdysone Receptor (EcR) autonomously controls germ cell differentiation in Drosophila ovary stem cells and cystoblasts, with distinct roles in self-renewal and differentiation.

Development · Jul 9, 2026Peer-reviewedDevelopmental Biology

Analysis of a hypomorphic mei-P26 mutation reveals coordination between developmental programming of germ cells and meiotic chromosome dynamics.

Joseph Terry, Ally Solomon, Amanda M. Powell, Patrick Terry, Oscar Bautista, Marty Landes, Erica Berent, Elizabeth Tweedie Ables, K. Nicole Crown

This study investigates how disrupting coordination between germ cell differentiation and meiosis in Drosophila affects meiotic chromosome dynamics using a hypomorphic mei-P26 mutation.

Genetics · Jun 27, 2026Peer-reviewedGenetics

A β-importin promotes fusome growth and distribution in Drosophila ovarian germ cells

Amanda M. Powell, Anna E. Williams, Elizabeth Tweedie Ables

This study identifies Tnpo-SR as a regulator of fusome morphogenesis in Drosophila germline cysts, showing that its depletion disrupts fusome structure and cyst organization.

bioRxiv · Mar 10, 2025 · PreprintDevelopmental Biology

β-importins Tnpo-SR and Cadmus and the small GTPase Ran promote ovarian cyst formation in Drosophila

Allison N. Beachum, Taylor D. Hinnant, Anna E. Williams, Amanda M. Powell, Elizabeth Tweedie Ables

This study identifies Ran and β-importins as critical regulators of germ cell cyst formation in Drosophila, showing they influence cell cycle dynamics and cyst stability without requiring mitotic spindle assembly.

Developmental Biology · Nov 28, 2022Peer-reviewedDevelopmental Biology

Ecdysone signaling promotes expression of multifunctional RNA binding proteins essential for ovarian germline stem cell self-renewal in Drosophila

Danielle S. Finger, Anna E. Williams, Vivian V. Holt, Elizabeth Tweedie Ables

The paper identifies hnRNPs regulated by ecdysone signaling that modulate BMP-dependent germline stem cell self-renewal in Drosophila.

Developmental Dynamics · Oct 29, 2022Peer-reviewedDevelopmental Biology