Todd G. Nystul

The paper identifies cytokinesis genes regulating ring canal patterning and follicle cell differentiation in Drosophila using deep learning and microscopy.

This study shows that the Ecdysone Receptor (EcR) autonomously controls germ cell differentiation in Drosophila ovary stem cells and cystoblasts, with distinct roles in self-renewal and differentiation.

This study identifies follicle cell dysfunction as a key driver of ovarian aging in Drosophila and shows that overexpressing Atg8a in these cells can reverse age-related reproductive decline.

This study creates a single-cell transcriptomic atlas of S. litura ovary, identifies key genes, and explores their role in reproduction and pest control.

The paper uses single-cell RNA sequencing to analyze bam mutant Drosophila ovaries, identifying distinct germ cell states and the role of gcrf1 in germ cell proliferation and fertility.

The paper uses single-cell transcriptomics to show that non-interacting signaling pathways prevent tumorigenesis by converging at the transcriptional level to block malignant cell behavior.

PROPEL is a postbaccalaureate program that trains scholars from underrepresented backgrounds in biomedical research, demonstrating its scalability and impact.

This paper introduces a high-throughput method for quantifying Drosophila fecundity using automated imaging and transfer systems, achieving high accuracy and efficiency in fecundity assays.

The paper shows that intracellular pH dynamics regulate intestinal stem cell lineage specification by promoting secretory or absorptive differentiation depending on pH levels.

This study uses scRNA-seq to identify genes regulating germ cell differentiation in Drosophila, highlighting eggplant as a key gene influenced by nutritional cues.

The paper creates a single-cell transcriptomic atlas of the adult fruit fly, identifying over 250 cell types and analyzing gene signatures and sexual dimorphism across tissues.

The paper constructs a single-cell RNA-seq atlas of the adult Drosophila ovary and identifies a new form of cellular plasticity in response to starvation.

This study identifies ae2 as a gene required for proper Drosophila ovary development and oogenesis, with its function linked to intracellular pH regulation.