Sebastian Fraune

Microbial genome functions explain metabolite-driven dysbiosis and Pseudomonas-associated ammonium toxicity in Hydra

This study shows that specific metabolites can shift Hydra's microbiome composition and function, leading to ammonia toxicity and disease-like phenotypes.

Extracellular Polymeric Substances Drive Curvibacter Host Adaptation and Co-Speciation with Hydra

This study shows Curvibacter bacteria co-evolve with Hydra through extracellular polymeric substances, enabling host-specific colonization and symbiosis stability.

Combined cellular and proteomics approach suggest differential processing of native and foreign vibrios in the sponge Halichondria panicea

The paper compares phagocytic processing of native and foreign Vibrio isolates in sponges, finding differential cellular and proteomic responses.

Oligonucleotide Library Assisted Sequence Mining Reveals Promoter Sequences With Distinct Temporal Expression Dynamics For Applications In Curvibacter SP. AEP1-3

The paper identifies active promoters in Curvibacter sp. AEP1-3 using an oligonucleotide library and flow cytometry, revealing distinct temporal expression dynamics across growth phases.

CATHI: An interactive platform for comparative genomics and homolog identification

CATHI provides an intuitive platform for comparative genomics and homolog identification, integrating tools like BLAST and MAFFT to streamline analysis for biologists without programming expertise.

Bacteria- and temperature-regulated peptides modulate beta-catenin signaling in Hydra

The paper identifies two peptides, Eco1 and Eco2, regulated by bacteria and temperature that modulate beta-catenin signaling and pattern formation in Hydra.