piRNAs safeguard splicing and RNA fidelity
Sehee Min, Johnny Cruz-Corchado, Veena Prahlad
This study shows piRNAs regulate pre-mRNA splicing in C. elegans to maintain transcript isoform fidelity and proteome integrity by delaying splice completion and modulating splice-site selection.
bioRxiv · Oct 27, 2025 · PreprintCell Biology