Author

Marek Trněný

Charles UniversityORCID 0000-0002-6952-6073Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Adéla BerkováiD· 1 shared Alexandra DolníkováiD· 1 shared Anežka Rajmonová· 1 shared Dana SoviljiD· 1 shared Jana SeňavováiD· 1 shared Karla SvobodováiD· 1 shared Kristýna KupcováiD· 1 shared Ladislav AnděraiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Adéla BerkováORCID

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1 paper

Recent·Most cited

Cancer BiologyBlood AdvancesPeer-reviewedAug 19, 2024

Impact of PIK3CA gain and PTEN loss on mantle cell lymphoma biology and sensitivity to targeted therapies

Nardjas Bettazová, Jana Seňavová, Kristýna Kupcová…·Ondřej Havránek

This study investigates how PIK3CA gain and PTEN loss affect MCL biology and drug response, finding reduced BCR dependence and increased therapy resistance.

6 citations

humanbulk RNA-seq