Author

Denise A. Hien

Rutgers, The State University of New JerseyORCID 0000-0002-6954-2882Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:imaging· 2 Research Focus:benchmarking· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Approach:matrix factorization· 1

Frequent Co-Authors

Cecilia A. HinojosaiD· 1 shared COGA Collaborators· 1 shared Danielle M. DickiD· 1 shared David Zald· 1 shared Holly E. PooreiD· 1 shared Joshua C. Zhao· 1 shared Joshua D. Barbosa· 1 shared Justine W. WelshiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperNeuroscience

Cecilia A. HinojosaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Substance use disorders exhibit unique and disorder specific genetic associations with externalizing and internalizing psychopathology

Holly E. Poore, Maia Choi, David Zald, Denise A. Hien, COGA Collaborators, Peter B. Barr, Danielle M. Dick

This study identifies genetic relationships between substance use disorders and externalizing/internalizing psychopathology, finding that internalizing contributes uniquely to SUD risk.

medRxiv · Jan 22, 2026 · PreprintGenetic & Genomic Medicine

Neural Domains Associated with Substance Use Disorders: A Systematic Review of Neuroimaging Studies

Cecilia A. Hinojosa, Siara I. Sitar, Joshua C. Zhao, Joshua D. Barbosa, Denise A. Hien, Justine W. Welsh, Negar Fani, Sanne J.H. van Rooij

This review examines neural domains linked to substance use disorders, finding altered activation in reward and inhibition processes but no trauma-exposed studies meeting criteria.

bioRxiv · Aug 11, 2023 · PreprintNeuroscience

Brain Anatomical Covariation Patterns Linked to Binge Drinking and Age at First Full Drink Prior to 21 Years

Yihong Zhao, Robert Todd Constable, Denise A. Hien, Tammy A. Chung, Marc Nicholas Potenza

The paper identifies a reproducible structural brain pattern linked to age at first full drink before 21, using JIVE analysis on neuroimaging data from two datasets.

NeuroImage Clinical · Dec 8, 2020Peer-reviewedNeuroscience