Persistent antigen is essential for sustaining Leishmania-specific memory CD4+ T cells and long-term immunity
Zhirong Mou, R. G. Zayats, Enitan S. Salako, Nnamdi M. Ikeogu, Somtochukwu Stella Onwah, Dong Liu, Hiroshi Hamana, Da Tan, Hiroyuki Kishi, Carson Leung, Janilyn Arsenio, Thomas T. Murooka, Jude Ezeh Uzonna
This study shows that persistent antigen is necessary for maintaining Leishmania-specific memory CD4+ T cells and long-term immunity.
bioRxiv · Jan 26, 2025 · PreprintImmunology