Antigen stimulation drives clonal expansion of latent CD4+ T cells using a full-length HIV latency reporter
Nnamdi M. Ikeogu, Oluwaseun Ajibola, Riley Greenslade…·Thomas T. Murooka
This study shows antigen stimulation drives clonal expansion of latent HIV-infected CD4+ T cells through TCR and co-stimulatory signals, with IL-7 and CD28 playing key roles.