Author

Can Yang Zhang

Tsinghua Shenzhen International Graduate SchoolORCID 0000-0002-6975-5781Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metagenomics· 1

Frequent Co-Authors

Xin‐Hui XingiD· 3 shared Long Huang· 2 shared Yi Wang· 2 shared Bing XuiD· 1 shared Changyue LiuiD· 1 shared Chong Zhang· 1 shared Chuhui WangiD· 1 shared Dongmei YuiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersMolecular Biology

Xin‐Hui XingORCID

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3 papers

Recent·Most cited

Deanticoagulated heparins drive a novel repair-secretory epithelial program to restore mucosal barrier in ulcerative colitis

Wei Hu, Zhen Kang Liu, Long Huang, Wen Zeng, Xiao Yi Ren, Yang Ji, Zheng Yang Song, Qin Xuan Zhou, Hai Hong Chen, Bing Xu, Can Yang Zhang, Chong Zhang, Peter Edward Lobie, Zhen Qing Zhang, Yun Sheng Yang, , Xin‐Hui Xing

The paper identifies NALHP/S6, a heparin derivative, as a glycan-based modulator that restores mucosal barrier function in ulcerative colitis by promoting a repair-secretory epithelial state.

bioRxiv · Aug 24, 2026 · PreprintMolecular Biology

Orally surface engineered probiotic system for ulcerative colitis therapy via modulating gut microbiota and immune homeostasis

Junyu Liu, Zhihao Fang, Xiaobin Li, Xiaopeng Zhang, Yun Chen, Fujia Kou, Long Huang, Huanxian Yang, Yilin Zheng, Yuqing Huang, Yi Wang, Xueqing Qiu, Jun Ge, Yong Qian, Xin‐Hui Xing, Can Yang Zhang

This paper develops a probiotic system for ulcerative colitis that enhances probiotic survival and colon targeting, modulates gut microbiota and immune responses, and provides a mathematical model for release dynamics.

Communications Biology · Feb 13, 2026Peer-reviewedMicrobiology

Detection of Frog virus 3 via the system integrating RPA-CRISPR/Cas12a-SPM with deep learning

Zhengyang Lei, Lijin Lian, Likun Zhang, Jiazhang Wei, Changyue Liu, Hong Liu, Ying Liu, Zhicheng Du, Xi Yuan, Xiaoyun Zhong, Ijaz Gul, Haihui Zhang, Chuhui Wang, Shiyao Zhai, Vijay Pandey, , Peiwu Qin

This paper develops a rapid, sensitive, and point-of-care FV3 detection system combining RPA-CRISPR/Cas12a with smartphone microscopy and deep learning, achieving 100% accuracy in classification.

bioRxiv · Aug 22, 2022 · PreprintMolecular Biology