Phosphatidic acid inhibits inositol synthesis by inducing nuclear translocation of IP6K1 and repression of myo-inositol-3-P synthase
Pablo Lazcano, Michael W. Schmidtke, Chisom Onu, Miriam L. Greenberg
This study shows that phosphatidic acid (PA) inhibits inositol synthesis by promoting nuclear translocation of IP6K1 and reducing MIPS expression through the AMPK-PLD pathway.
bioRxiv · Feb 21, 2022 · PreprintMolecular Biology