Pharmacology & ToxicologyEnvironmental Science & TechnologyPeer-reviewed
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Leveraging zebrafish embryo phenotypic observations to advance data-driven analyses in toxicology
Paul Michaelis, Nils Klüver, Silke Aulhorn…·Wibke Busch
A structured zebrafish embryo toxicity database (INTOB, 638 experiments) enabled control-quality tests, dose-response modeling and phenotype-fingerprint clustering of 47 substances (133 experiments); literature data proved unsuitable for meta-analysis.
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