Author

Brock A. Humphries

University of MichiganORCID 0000-0002-6992-3394Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alyssa C. CutteriD· 1 shared Anne Zhang· 1 shared Gary D. LukeriD· 1 shared Johanna M. BuschhausiD· 1 shared Kenneth K. Y. HoiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

Alyssa C. CutterORCID

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1 paper

Recent·Most cited

Cancer BiologyScientific ReportsPeer-reviewedAug 13, 2025

Substrate stiffness regulates triple-negative breast cancer signaling through CXCR4 receptor dynamics

Kenneth K. Y. Ho, Johanna M. Buschhaus, Anne Zhang…·Gary D. Luker

This study shows that substrate stiffness affects CXCR4 and EGFR expression and signaling in TNBC cells, promoting Akt and ERK activation and migration.

7 citations

humanbulk RNA-seq