Jesús Muñoz‐Estrada

The paper uses proteomic analysis of APP-London mutant neurons to show early cholesterol remodeling and altered A beta secretion without changes in total cholesterol.

This paper develops a platform combining robotic proteomics and AI to enable scalable drug mechanism discovery through high-throughput data analysis and hypothesis generation.

scTransient detects transient gene expression events in single-cell data by combining trajectory inference with wavelet analysis, revealing previously unreported biological spikes in three datasets.

SMAD-MS enables rapid single-injection multi-omics analysis of proteomics, metabolomics, and lipidomics without liquid chromatography, achieving high throughput and efficiency.

The paper shows that extended NGN2 expression in iPSCs improves neuronal culture purity by reducing heterogeneity caused by suboptimal differentiation.