Author

Jonathan R. Bradley

Florida State UniversityORCID 0000-0002-7000-2576Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:GWAS / association mapping· 2 Assay:bulk RNA-seq· 1 Research Focus:deconvolution· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:imputation· 1

Frequent Co-Authors

Chong WuiD· 3 shared Lang WuiD· 2 shared Hong‐Wen DengiD· 1 shared Hunter J. MeltoniD· 1 shared Yanming LiiD· 1 shared Ye Eun BaeiD· 1 shared Zichen ZhangiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 12 mutual co-author links

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3 shared papersGenomics

Chong WuORCID

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3 papers

Recent·Most cited

GenomicsBiometricsPeer-reviewedMar 19, 2026

A Zero-Inflated Hierarchical Generalized Transformation Model to Address Non-Normality in Spatially-Informed Cell-Type Deconvolution

Hunter J. Melton, Jonathan R. Bradley, Chong Wu

This paper develops a zero-inflated hierarchical generalized transformation model to improve cell-type deconvolution in spatial transcriptomics data from oral squamous cell carcinomas.

DOI 10.1093/biomtc/ujag055

humanspatial transcriptomics

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Genetic & Genomic MedicineNature CommunicationsPeer-reviewedOct 25, 2022

SUMMIT: An integrative approach for better transcriptomic data imputation improves causal gene identification

Zichen Zhang, Ye Eun Bae, Jonathan R. Bradley…·Chong Wu

SUMMIT improves transcriptomic data imputation and TWAS power by using large eQTL summary datasets, identifying 11 causal genes for COVID-19 severity.

24 citations

humanbulk RNA-seq

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GenomicsBioinformaticsPeer-reviewedJan 20, 2021

A gene-level methylome-wide association analysis identifies novel Alzheimer's disease genes

Chong Wu, Jonathan R. Bradley, Yanming Li…·Hong‐Wen Deng

This paper introduces a gene-level methylome-wide association analysis method called CMO that identifies novel Alzheimer's disease genes by integrating DNA methylation and enhancer-promoter interactions with GWAS data.

12 citations

humanDNA methylation

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