Author

Xiaotian Du

Second Affiliated Hospital of Zhejiang UniversityORCID 0000-0002-7000-7828Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Dongmei WuiD· 1 shared Dongsheng YuiD· 1 shared Hongwei OuyangiD· 1 shared Jiajie HuiD· 1 shared Jiasheng WangiD· 1 shared Junfen Ji· 1 shared Youzhi CaiiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperPathology

Dongmei WuORCID

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1 paper

Recent·Most cited

PathologybioRxivPreprintApr 15, 2023

Reprogramming of lipid secretome in senescent synovial fibroblasts ameliorate osteoarthritis development

Jiajie Hu, Dongsheng Yu, Dongmei Wu…·Hongwei Ouyang

This study identifies RCAN1+IL1+ senescent synovial fibroblasts as drivers of osteoarthritis by secreting saturated fatty acids, and shows that targeting RCAN1 reduces OA progression in mice.

3 citations

humanmouse

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