Patrick Jackson

Rev-RRE activity modulates HIV-1 replication and latency reactivation: Implications for viral persistence and cure strategies

This study shows that variations in Rev-RRE activity affect HIV-1 replication and latency reactivation, suggesting it could be a target for cure strategies.

A novel retroviral vector system to analyze expression from mRNA with retained introns using fluorescent proteins and flow cytometry

This paper describes a novel retroviral vector system to measure the export and translation efficiency of mRNAs with retained introns using fluorescent proteins and flow cytometry.

Evolution of the HIV-1 RRE during natural infection reveals nucleotide changes that correlate with altered structure and increased activity over time

The paper tracks RRE sequence and functional changes in a single HIV-infected patient over six years, finding increased activity and structural changes over time.