David M. Rekosh

The paper identifies and characterizes functional and trans-dominant negative HERV-K (HML-2) Rec proteins, revealing their diverse regulatory roles in post-transcriptional processes.

This study shows that variations in Rev-RRE activity affect HIV-1 replication and latency reactivation, suggesting it could be a target for cure strategies.

This paper describes a novel retroviral vector system to measure the export and translation efficiency of mRNAs with retained introns using fluorescent proteins and flow cytometry.

The paper tracks RRE sequence and functional changes in a single HIV-infected patient over six years, finding increased activity and structural changes over time.