Molecular BiologyNucleic Acids ResearchPeer-reviewed
Eukaryotic RNA-guided endonucleases evolved from a unique clade of bacterial enzymes
Peter H. Yoon, Petr Skopintsev, Honglue Shi…·Jennifer A. Doudna
The paper traces the evolutionary origin of eukaryotic RNA-guided endonucleases, showing they evolved from a specific clade of bacterial IS607 TnpB enzymes.
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