Author

Jasmine Amerasekera

University of California, Los Angeles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 3 Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:whole-genome sequencing· 4 Organism:Arabidopsis· 3 Assay:DNA methylation· 3 Research Focus:gene regulatory network inference· 3 Research Focus:clustering· 2 Organism:plant (other)· 2 Research Focus:variant calling· 2

Frequent Co-Authors

Steven E. JacobseniD· 5 shared Honglue ShiiD· 4 shared Jennifer A. DoudnaiD· 4 shared Maris KamaluiD· 4 shared Kamakshi VohraiD· 3 shared Marena I. TrinidadiD· 3 shared Trevor J. WeissiD· 3 shared Benjamin A. AdleriD· 2 shared

Activity by Year

2023-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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5 shared papersPlant Biology

Steven E. JacobsenORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Stepwise DNA unwinding gates TnpB genome-editing activity

Zehan Zhou, Iren Saffarian-Deemyad, Honglue Shi, Trevor Weiss, Muhammad Moez ur-Rehman, Kamakshi Vohra, Petr Skopintsev, Peter H. Yoon, Marena I. Trinidad, Conner J. Langeberg, Maris Kamalu, Jasmine Amerasekera, Yuxing Zhou, Erin E. Doherty, Kevin Aris, , Jennifer A. Doudna

Ymu1 TnpB unwinds DNA via a long-lived partially unwound intermediate before a rarely stable open state; the WFR triple variant stabilizes both, boosting plant editing.

Molecular Cell · Aug 1, 2026Peer-reviewedBiochemistry✦ In-depth digest

Virus induced transgene- and tissue culture-free heritable genome editing in tomato

Ye Liu, Trevor J. Weiss, Jin Hee Lee, Jessica Powell, Shi Ying Charlize Choo, Elnaz Roshannai, Maris Kamalu, Jasmine Amerasekera, Suhua Feng, Steven E. Jacobsen

This paper develops a virus-based system for transgene- and tissue culture-free heritable genome editing in tomato, achieving somatic editing and mutant progeny without transgenic materials.

Proceedings of the National Academy of Sciences · Jun 4, 2026Peer-reviewedPlant Biology

Efficient transgene-free multiplexed genome editing via viral delivery of an engineered TnpB.

Trevor J. Weiss, Maris Kamalu, Honglue Shi, Gabriel Wirnowski, Alice Ingelsson, Jasmine Amerasekera, Kamakshi Vohra, Marena I. Trinidad, Z. M. Li, Emily dos Santos Galante Freitas, Noah Steinmetz, Charlie Ambrose, Kerry Chen, Jennifer A. Doudna, Steven E. Jacobsen

The paper improves a virus-mediated genome editing method in plants by using multiple gRNAs and an enhanced TnpB variant for efficient multiplexed editing.

Plant Biotechnology Journal · Mar 17, 2026Peer-reviewedPlant Biology

Viral delivery of an RNA-guided genome editor for transgene-free germline editing in Arabidopsis

Trevor J. Weiss, Maris Kamalu, Honglue Shi, Zheng Li, Jasmine Amerasekera, Zhenhui Zhong, Benjamin A. Adler, Michelle M Song, Kamakshi Vohra, Gabriel Wirnowski, Sidharth Chitkara, Charlie Ambrose, Noah Steinmetz, Ananya Sridharan, Diego Sahagun, , Steven E. Jacobsen

This paper engineers a plant virus to deliver a compact CRISPR-Cas system for transgene-free germline editing in Arabidopsis.

Nature Plants · Apr 22, 2025Peer-reviewedPlant Biology

Eukaryotic RNA-guided endonucleases evolved from a unique clade of bacterial enzymes

Peter H. Yoon, Petr Skopintsev, Honglue Shi, Lin-Xing Chen, Benjamin A. Adler, Muntathar J. Al-Shimary, Rory J. Craig, Kenneth J. Loi, Evan C. DeTurk, Zheng Li, Jasmine Amerasekera, Marena I. Trinidad, Hunter M. Nisonoff, Kai Chen, Arushi Lahiri, , Jennifer A. Doudna

The paper traces the evolutionary origin of eukaryotic RNA-guided endonucleases, showing they evolved from a specific clade of bacterial IS607 TnpB enzymes.

Nucleic Acids Research · Nov 16, 2023Peer-reviewedMolecular Biology