Author

Danielle M. Spice

Western UniversityORCID 0000-0002-7038-0067Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Gregory Mitchell KellyiD· 2 shared Gilles LajoieiD· 1 shared Joshua G. DierolfiD· 1 shared Tyler T. CooperiD· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 4 mutual co-author links

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2 shared papersDevelopmental Biology

Gregory Mitchell KellyORCID

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2 papers

Recent·Most cited

Developmental BiologyCellular SignallingPeer-reviewedOct 3, 2022

Never in Mitosis Kinase 2 regulation of metabolism is required for neural differentiation

Danielle M. Spice, Tyler T. Cooper, Gilles Lajoie, Gregory Mitchell Kelly

This study shows Nek2 regulates neural differentiation by controlling metabolism, specifically preventing HIF1 stabilization to enable oxidative phosphorylation.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky

Developmental BiologyStem Cells and DevelopmentPeer-reviewedSep 14, 2022

Sufu regulation of Hedgehog signaling in P19 cells is required for proper astrocyte differentiation

Danielle M. Spice, Joshua G. Dierolf, Gregory Mitchell Kelly

The paper investigates SUFU's role in regulating Hedgehog signaling during astrocyte differentiation in P19 cells, finding that SUFU is necessary for proper timing and proportion of astrocyte differentiation.

3 citations

mousebulk RNA-seq

𝕏 PostBluesky