BioengineeringbioRxivPreprint
Systematic molecular glue drug discovery with a high-throughput effector protein remodeling platform
Jia Lu, Kate Stuart, Rebecca Teague…·Benedict C. S. Cross
This paper introduces a platform for discovering molecular glue degraders by engineering effector proteins to enable systematic identification of new small molecule degraders targeting GSPT1.
DOI 10.1101/2025.07.17.664724