Systems BiologyiSciencePeer-reviewed
Synthetic lethality-based prediction of anti-SARS-CoV-2 targets
Lipika R. Pal, Kuoyuan Cheng, Nishanth Ulhas Nair…·Eytan Ruppin
The paper predicts anti-SARS-CoV-2 targets by identifying synthetic lethal partners of host genes altered during infection, validated through CRISPR-Cas9 screens and siRNA experiments.
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