Laura Martin‐Sancho

This paper identifies a small molecule, M4, that inhibits influenza A and B replication by targeting the host protein STARD7, preventing vRNP nuclear export and demonstrating synergistic antiviral effects with baloxavir in mice.

This study identifies host proteins co-opted by influenza A virus polymerase for transcription or replication using differential interactome screening.

This study identifies critical human host factors involved in SARS-CoV-2 multicycle replication through a genome-scale siRNA screen and validates potential antiviral targets.

The paper predicts anti-SARS-CoV-2 targets by identifying synthetic lethal partners of host genes altered during infection, validated through CRISPR-Cas9 screens and siRNA experiments.

This study maps the SARS-CoV-2 virus-host interactome using BioID in A549 cells and provides a public resource for analyzing host-viral protein associations.

The paper uses genome-scale metabolic modeling to identify SARS-CoV-2-induced metabolic changes and predict antiviral targets validated through drug and genetic screens.

SARS-CoV-2 infects and kills neural cells in iPSC-derived human brain organoids and impairs synaptogenesis; the approved antiviral sofosbuvir is reported to reverse both effects.