Author

Lauren Y. Shields

Gladstone InstitutesORCID 0000-0002-7071-7934Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

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Dominik HaddadiD· 1 shared Huihui LiiD· 1 shared Hwajin KimiD· 1 shared Joseph H. GarciaiD· 1 shared Keith A. VosseliD· 1 shared Ken NakamuraiD· 1 shared Kevin Nguyen· 1 shared Meredith CalvertiD· 1 shared

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2021-2021 · peak 1/yr

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1 shared paperNeuroscience

Dominik HaddadORCID

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1 paper

Recent·Most cited

NeuroscienceJournal of Biological ChemistryPeer-reviewedJan 1, 2021

Mitochondrial fission is a critical modulator of mutant APP-induced neural toxicity

Lauren Y. Shields, Huihui Li, Kevin Nguyen…·Ken Nakamura

This study shows that loss of Drp1 in neurons worsens memory deficits in mice with mutant hAPP, revealing a protective role of mitochondrial fission against hAPP-induced pathology.

22 citations

mouseexperimental assay

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