BiochemistryNature CommunicationsPeer-reviewed
Selective degradation of BRD9 by a DCAF16-recruiting targeted glue: mode of action elucidation and in vivo proof of concept
Scott J. Hughes, Wojciech J. Stec, Colin T. R. Davies…·Andrea Testa
The paper identifies a potent BRD9 degrader, AMPTX-1, which selectively recruits BRD9 to DCAF16, leading to its degradation in vivo.
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