RESM: Capturing sequence and structure encoding of RNAs by mapped transfer learning from ESM (evolutionary scale modeling) protein language model
Yikun Zhang, Hao Zhang, Guowei Li, He Wang, Xing Zhang, Xu Hong, Ting-Ting Zhang, Liangsheng Wen, Yu Zhao, Jiuhong Jiang, Jie Chen, Yanjun Chen, Liwei Liu, Jian Zhan, Yaoqi Zhou
RESM improves RNA sequence-structure-function prediction by transferring knowledge from protein language models, outperforming existing models in multiple tasks.
bioRxiv · Aug 9, 2025 · PreprintBioinformatics