Yu Zhao

The paper predicts ROR1 and CAV1 expression from whole-exome sequencing data to assess response to B013 plus nab-paclitaxel in triple-negative breast cancer, showing agreement with observed responses in 9 out of 10 patients.

The paper identifies a causal allele in the CD40 locus and demonstrates context-specific trans-effects in B cells using CITE-seq and CRAFT-seq.

Hypoimmunogenic human motor neurons induced from iPSCs in vivo reform neuromuscular junctions and ameliorate ALS disease in pig and rabbit models.

RESM improves RNA sequence-structure-function prediction by transferring knowledge from protein language models, outperforming existing models in multiple tasks.