Jorge Júlvez

This paper combines constraint-based and kinetic metabolic models to improve flux bounds in genome-scale models, enhancing predictive accuracy for E. coli growth and citramalate production.

The paper develops metabolic models for M. leprae and M. abscessus to identify potential drug targets, highlighting unique pathways for precision medicine.

The paper compares metabolic pathways in three mycobacteria to identify common drug targets and assess their druggability.