Stephen G. Oliver

This study identifies conditions for observing sulfide-induced invasive growth in wine yeast and shows genetic and environmental factors influence this behavior.

This paper combines constraint-based and kinetic metabolic models to improve flux bounds in genome-scale models, enhancing predictive accuracy for E. coli growth and citramalate production.

The paper constructs a synthetic yeast chromosome XI and demonstrates how non-coding DNA modifications affect cell fitness, enabling on-demand extrachromosomal circular DNA formation.

The paper describes PomBase, a database for fission yeast, and highlights its features and contributions to the model organism database community.

The paper shows that yeast lacking one copy of ARH1 exhibits metabolic and transcriptional changes similar to those in Parkinson’s disease, suggesting yeast as a model for studying disease mechanisms.

The paper uses a yeast model to analyze multi-omic data from OPTN overexpression, finding distinct genetic and metabolic responses to different ALS-linked genes.

The paper identifies conserved but unstudied proteins in yeast and human, highlighting their potential importance and proposing strategies to better characterize them.

The paper compares metabolic pathways in three mycobacteria to identify common drug targets and assess their druggability.

The paper uses constraint-based modeling to estimate enzyme abundance levels in yeast iron metabolism and identifies a mutualistic relationship between yeast and Streptomyces coelicolor.

The paper analyzes transcriptional regulatory networks in yeast to identify novel features of gene regulation in protein transactions, finding that transcriptional regulation is underrepresented and controlled by few regulators.

The paper shows that differential mobility of chromatin segments, influenced by protein occupancy, drives 3D genome organisation in yeast.