Author

Fayal Abderemane-Ali

University of California, Los AngelesORCID 0000-0002-7097-1684Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Daniel L. MinoriD· 1 shared Dowson YangiD· 1 shared Evelina GromilinaiD· 1 shared Fiona B. NaughtoniD· 1 shared Hayeon YangiD· 1 shared Michael GrabeiD· 1 shared Mridhula Joan ThyagarajaniD· 1 shared Seil JangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiophysics

Daniel L. MinorORCID

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2 papers

Recent·Most cited

Batrachotoxin Sensitive Sodium Channels in Toxic Birds Challenge "Target Mutation" Strategy of Toxin Autoresistance

Evelina Gromilina, Zhiying Jia, Mridhula Joan Thyagarajan, Hayeon Yang, Dowson Yang, Fayal Abderemane-Ali

The paper tests the 'target mutation' hypothesis for batrachotoxin autoresistance in toxic birds and finds substitutions do not confer resistance, supporting a sequestration model.

iScience · Aug 1, 2026Peer-reviewedBiophysics

Structure of the human K2P13.1(THIK-1) channel reveals a novel hydrophilic pore restriction and lipid cofactor site

Shatabdi Roy-Chowdhury, Seil Jang, Fayal Abderemane-Ali, Fiona B. Naughton, Michael Grabe, Daniel L. Minor

This paper presents cryo-EM structures of human K2P13.1 (THIK-1) revealing a novel hydrophilic pore restriction and lipid cofactor site, with implications for modulator development.

Nature Structural & Molecular Biology · Feb 26, 2025Peer-reviewedBiophysics