Author

Lieven Lagae

Universitair Ziekenhuis LeuvenORCID 0000-0002-7118-0139Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1

Frequent Co-Authors

Sarah WeckhuyseniD· 2 shared Aleksei RakitiniD· 1 shared Alison AndersoniD· 1 shared Alison Anne HitchcockiD· 1 shared Ana Antonic‐BakeriD· 1 shared Andrea JorgenseniD· 1 shared Andreja AvberšekiD· 1 shared Anja C. M. Sonsma· 1 shared

Activity by Year

2016-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Sarah WeckhuysenORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicineNeurologyPeer-reviewedJan 14, 2026

Transcription factor binding and individual genetic risk for valproate teratogenicity

Alison Anderson, Piero Perucca, Elena Vianca…·Sameer M. Zuberi

The paper investigates how genetic variants affecting transcription factor binding contribute to valproate-induced birth defects and identifies EP300 as a key regulator involved in this process.

3 citationstop 1%

humanwhole-exome sequencing

𝕏 PostBluesky

NeurosciencebioRxivPreprintJul 22, 2025

Kv7.2 Loss-of-Function Causes Early Hyperexcitability and Network Remodeling

Nina Dirkx, Mark D. Kaji, Els De Vriendt…·Sarah Weckhuysen

This study shows that KCNQ2 loss-of-function causes early hyperexcitability and network remodeling in human neurons, with biphasic changes in function, gene expression, and structure.

DOI 10.1101/2025.07.22.664856

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintNov 15, 2016

Antenatal maternal anxiety modulates the BOLD response in 20-year old adolescents during an endogenous cognitive control task

Maarten Mennes, Bea R.H. Van den Bergh, Stefan G. Sunaert…·Peter L. J. Stiers

This study finds that prenatal maternal anxiety affects brain activity in adolescents during a cognitive control task, specifically modulating prefrontal cortical responses to task manipulations.

3 citations

humanimaging

𝕏 PostBluesky