Christopher Witzany

The paper models how plasmid and chromosomal compensation affect the spread of antimicrobial resistance, finding short-term plasmid-borne compensation dominates but long-term chromosomal or combined compensation leads to multidrug resistance.

This study shows that the innate immune system, not antibiotic type or bacterial resistance, determines treatment success in infections using Galleria mellonella and Staphylococcus aureus.

This study uses Galleria mellonella larvae to test hypotheses about innate immunity's role in bacterial infections and shows bacteriostatic drugs and phages are as effective as bactericidal antibiotics.

This study shows that random antimicrobial peptide mixtures reduce resistance evolution in Pseudomonas aeruginosa compared to single peptides, preventing cross-resistance and maintaining drug sensitivity.