FXR2 Promotes Autophagic Clearance of Sindbis Virus Capsid and Protects Against Viral Encephalitis
Vibha Singh, Phillip W Dryden, Woo Yong Chang, Zhongju Zou, Yanghong Gu, David Lee Nelson, Tao Wang, Josephine W. Thinwa, Tiffany A. Reese
This study identifies FXR2 as a mediator of autophagy that clears Sindbis virus capsid and protects against viral encephalitis by reducing viral protein toxicity.
bioRxiv · Oct 27, 2026 · PreprintMicrobiology