Valentina Salsi

The paper identifies a stage-specific chromatin accessibility state in FSHD myoblasts that resolves during differentiation, showing architectural remodeling uncoupled from DUX4 target loci.

This paper identifies NF-YA alternative splicing as a driver of glutamine metabolism in colorectal cancer, revealing a therapeutic target for aggressive subtypes.

This study identifies a family of lncRNAs, including FRG2A, whose overexpression in FSHD patients disrupts nucleolar architecture and reduces protein synthesis, linking FSHD to muscle wasting.

The paper investigates how D4Z4 repeat length and genotoxic stress affect RNA stability and chromatin association of genes at the 4q35 locus.

This study uses pan-genomic data to analyze D4Z4 repeats and CpG methylation in FSHD, finding low methylation correlates with SMCHD1 variants but not clinical phenotypes.