Author

Minglei Shu

National Supercomputing Center in JinanORCID 0000-0002-7136-1538Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:dimensionality reduction· 1 Organism:human· 1 Approach:matrix factorization· 1

Frequent Co-Authors

Baibin Bi· 1 shared Cuiling LiiD· 1 shared Di WuiD· 1 shared Di YuiD· 1 shared Feng Shi· 1 shared Fengqin WangiD· 1 shared Han ZhaoiD· 1 shared Haobo ZhangiD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Baibin Bi

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2 papers

Recent·Most cited

Dimensionality reduction by UMAP reinforces sample heterogeneity analysis in bulk transcriptomic data

Yang Yang, Hongjian Sun, Yu Zhang, Tiefu Zhang, Jialei Gong, Yunbo Wei, Yong‐Gang Duan, Minglei Shu, Yuchen Yang, Di Wu, Di Yu

This study compares dimensionality reduction methods for bulk transcriptomic data, finding UMAP better preserves sample neighbourhood and clustering accuracy than PCA, MDS, and t-SNE.

Cell Reports · Jul 1, 2021Peer-reviewedBioinformatics

Widespread noncoded amino acids in human proteome

Jing-Hua Yang, Xinjun Chen, Jing Gong, Xin Lv, Han Zhao, Cuiling Li, Baibin Bi, Fengqin Wang, Shengnan Sun, Xingyuan Wang, Haobo Zhang, Tao Huang, Kazem M. Azadzoi, Feng Shi, Xianglong Kong, , Zi‐Jiang Chen

The paper identifies 571 noncoded amino acids in the human sperm proteome, revealing novel residues and disease associations through mass spectrometry and exon sequencing.

bioRxiv · Apr 1, 2018 · PreprintMolecular Biology