Aneuploidy Promotes Intestinal Dysplasia in Drosophila
Luís Pedro Resende, Augusta Monteiro, Rita Brás, Tatiana Lopes, Cláudio E. Sunkel
This study shows that Drosophila intestinal stem cells tolerate aneuploidy without apoptosis, leading to tissue dysplasia through increased proliferation and lineage skewing.
The Journal of Cell Biology · Oct 3, 2018Peer-reviewedDevelopmental Biology