Author

John S.A. Chrisinger

Washington University in St. LouisORCID 0000-0002-7138-0923Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Assay:snRNA-seq· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Carina Anja DehneriD· 2 shared Aadel A. ChaudhuriiD· 1 shared AeRang KimiD· 1 shared Alexander C. PaniD· 1 shared Amy E. ArmstrongiD· 1 shared Andrea M. GrossiD· 1 shared Andrea Nicole LucasiD· 1 shared Angela C. HirbeiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Carina Anja DehnerORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 7, 2026

Identification and Characterization of Neoplastic Cells in Keratin-Positive Giant Cell-Rich Tumors

Maarten van der Linde, John S.A. Chrisinger, Elizabeth G. Demicco…·David G.P. van IJzendoorn

This paper uses single-nuclei RNA sequencing and spatial transcriptomics to characterize KPGCT, showing neoplastic cells express HMGA2::NCOR2 fusions and activate the hippo pathway, driving CSF1 production and macrophage recruitment.

1 citation

humansnRNA-seq

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Genetic & Genomic MedicineClinical Cancer ResearchPeer-reviewedAug 2, 2024

Early detection of malignant and pre-malignant peripheral nerve tumors using cell-free DNA fragmentomics

R. Taylor Sundby, Jeffrey J. Szymanski, Alexander C. Pan…·Jack F. Shern

This study uses plasma cfDNA fragmentomics to distinguish malignant, pre-malignant, and non-malignant NF1-associated peripheral nerve sheath tumors.

26 citationstop 2%

humanDNA methylation

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