Author

Maarten van der Linde

Leiden University Medical CenterORCID 0009-0009-6580-5137Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Organism:human· 2 Assay:spatial transcriptomics· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

David G.P. van IJzendoorniD· 2 shared Magdalena MatusiakiD· 2 shared Carina Anja DehneriD· 1 shared Chenchen ZhuiD· 1 shared Chunfang ZhuiD· 1 shared Elizabeth G. DemiccoiD· 1 shared Gregory W. CharvilleiD· 1 shared Inge H. Briaire‐de BruijniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBioinformatics

David G.P. van IJzendoornORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintAug 21, 2026

Resolving the immune response across clonal cancer evolution in situ with Atera whole transcriptome profiling

Shaocheng Wu, Mohita Mahajan, Maarten van der Linde…·Magdalena Matusiak

This study evaluates Atera, a spatial transcriptomics platform, showing its ability to resolve clonal cancer evolution and immune response in situ using DCIS samples.

1 citation

humanspatial transcriptomics

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Cancer BiologybioRxivPreprintApr 7, 2026

Identification and Characterization of Neoplastic Cells in Keratin-Positive Giant Cell-Rich Tumors

Maarten van der Linde, John S.A. Chrisinger, Elizabeth G. Demicco…·David G.P. van IJzendoorn

This paper uses single-nuclei RNA sequencing and spatial transcriptomics to characterize KPGCT, showing neoplastic cells express HMGA2::NCOR2 fusions and activate the hippo pathway, driving CSF1 production and macrophage recruitment.

1 citation

humansnRNA-seq

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