GWASHub is a cloud-based platform for GWAS meta-analysis that automates data handling, QC, and analysis workflows to improve reproducibility and reduce researcher burden.

medRxiv · Oct 21, 2025 · PreprintGenetic & Genomic Medicine

The Neurodegenerative Disease Knowledge Portal: Propelling Discovery Through the Sharing of Neurodegenerative Disease Genomic Resources

Allison Ann Dilliott, Maria C. Costanzo, Sara Bandrés‐Ciga, Cornelis Blauwendraat, Bradford H. Casey, Quy Hoang, Hirotaka Iwaki, Dongkeun Jang, Jonggeol Jeffrey Kim, Hampton L. Leonard, Kristin S. Levine, Mary B. Makarious, Trang Thi Huyen Nguyen, Guy Armand Rouleau, Andrew Singleton, , Sali M.K. Farhan

The paper introduces the Neurodegenerative Disease Knowledge Portal (NDKP), an open-science platform aggregating genomic datasets for neurodegenerative diseases to enable collaborative analysis and discovery.

Neurology Genetics · Feb 21, 2025Peer-reviewedGenetic & Genomic Medicine

An Effector Index to Predict Causal Genes at GWAS Loci

Vincenzo Forgetta, Lai Jiang, Nicholas A. Vulpescu, Megan S. Hogan, Siyuan Chen, John A. Morris, Stepan Grinek, Christian Benner, Dongkeun Jang, Quy Hoang, Noël P. Burtt, Jason A. Flannick, Mark I. McCarthy, Eric B. Fauman, Celia M.T. Greenwood, , John Brent Richards

The paper introduces the Effector Index, an algorithm to predict causal genes at GWAS loci using genomic features, achieving 85% AUC in type 2 diabetes validation.

Human Genetics · Feb 11, 2022Peer-reviewedBioinformatics