BiophysicsProteins Structure Function and BioinformaticsPeer-reviewed
Responses to ligand binding in the bacterial DNA sliding clamp beta-clamp manifest in dynamic allosteric effects
Signe Simonsen, Andreas Prestel, Eva Christina Østerlund…·Birthe Brandt Kragelund
This study investigates how ligand binding affects the dynamics of the bacterial DNA sliding clamp beta-clamp using NMR and hydrogen-deuterium exchange mass spectrometry, revealing dynamic allosteric effects.