Andreas Prestel

Cooperativity, dynamics, and the free-energy surfaces of charge-patterned IDPs

This study examines how charge patterning affects the conformational behavior and dynamics of intrinsically disordered proteins using experimental techniques and simulations.

Responses to ligand binding in the bacterial DNA sliding clamp beta-clamp manifest in dynamic allosteric effects

This study investigates how ligand binding affects the dynamics of the bacterial DNA sliding clamp beta-clamp using NMR and hydrogen-deuterium exchange mass spectrometry, revealing dynamic allosteric effects.

The SH Protein of Mumps Virus is a Druggable Pentameric Viroporin

This study identifies the mumps virus SH protein as a pentameric viroporin and shows it functions as a chloride channel inhibited by BIT225.

Distinction between small RNA-bound and free ARGONAUTE via an N-terminal protein-protein interaction site

The paper identifies an N-terminal region in AGO proteins that is accessible in the RNA-free state and mediates specific degradation through interaction with ATI1.

The Arabidopsis autophagy cargo receptors ATI1 and ATI2 bind to ATG8 via intrinsically disordered regions and are post-translationally modified upon ATG8 interaction

This paper investigates the molecular properties of Arabidopsis autophagy cargo receptors ATI1 and ATI2, showing their intrinsically disordered regions and post-translational modifications upon ATG8 interaction.