Molecular BiologybioRxiv
Oxidized low-density lipoprotein potentiates angiotensin II-induced Gq activation through the AT1-LOX1 receptor complex: Implications for renal dysfunction
Jittoku Ihara, Yibin Huang, Yoichi Takami…·Koichi I. Yamamoto
This study shows oxLDL enhances Ang II-induced Gq signaling via the AT1-LOX1 complex, contributing to renal dysfunction in CKD and hypertension.
3 citations