Author

Yibin Huang

The University of Texas Southwestern Medical CenterORCID 0000-0002-5016-3559Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Akemi KakinoiD· 1 shared Bo Li· 1 shared Cheng WangiD· 1 shared Chieko MineoiD· 1 shared DENNIS BURNS· 1 shared Hikari Takeshita· 1 shared Hiromi RakugiiD· 1 shared Hiroshi AkasakaiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Akemi KakinoORCID

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2 papers

Recent·Most cited

Coronary Artery Disease Transcriptomics Reveals Two Drivers of the Endothelial Cell SR-BI Expression and LDL Transport that Underlie Atherosclerosis

Linzhang Huang, Yibin Huang, Jiayu Zhu, Jun Peng, Kenian Chen, Ken L. Chambliss, Qinbo Zhou, Ryan J. Vela, DENNIS BURNS, Bo Li, Matthias Peltz, Yun Hua Fang, Lin Xu, Chieko Mineo, Philip W. Shaul

This study identifies two factors, hypercholesterolemia and disturbed blood flow, that upregulate endothelial SR-BI to drive LDL transport and atherosclerosis.

bioRxiv · Aug 6, 2026 · PreprintCell Biology

Oxidized low-density lipoprotein potentiates angiotensin II-induced Gq activation through the AT1-LOX1 receptor complex: Implications for renal dysfunction

Jittoku Ihara, Yibin Huang, Yoichi Takami, Yoichi Nozato, Toshimasa Takahashi, Akemi Kakino, Cheng Wang, Ziwei Wang, Yu Guo, Weidong Liu, Nanxiang Yin, Ryoichi Ohara, Taku Fujimoto, Shino Yoshida, Kazuhiro Hongyo, , Koichi I. Yamamoto

This study shows oxLDL enhances Ang II-induced Gq signaling via the AT1-LOX1 complex, contributing to renal dysfunction in CKD and hypertension.

bioRxiv · May 13, 2024Molecular Biology